Zion Market Research has published a new report titled “Macrolide Drugs Market by Drug Type (14-membered ring agents, 14-membered ring agents (Azalides), 16-membered ring agents, and Ketolides), By Distribution Channels (Hospital pharmacies, Clinics, Hospitals, Retail pharmacies, and Online pharmacies): Global Industry Perspective, Comprehensive Analysis and Forecast, 2018 – 2024 ”. According to the report, global macrolide drugs market was valued at approximately USD 6.14 billion in 2017 and is expected to generate revenue from around USD 7.66 billion by end of 2024, growing at a CAGR of around 3.2% between 2018 and 2024.
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Macrolides are a class of antibacterial drugs that contain large macrocyclic lactone ring. One or more deoxy-sugars, usually desosamine and cladinosis are attached to the macrocyclic lactone ring. The macrocyclic lactone ring generally is 14, 15 or 16 membered. Antibiotic macrolides are derived from Saccharopolyspora erythracea. Macrolides inhibit protein synthesis in bacteria. The inhibition of protein synthesis is carried out by binding to the 50s ribosome. Macrolides are more effective against gram-positive bacteria as well as intracellular pathogens such as Chlamydia, Mycoplasma, and Legionella. Macrolides primarily act as bacteriostatic agents opposite several strains of Moxicella, Staphylococci Streptococci, Corynebacteria, Clostridia, Listeria, Neisseria meningitides, and Haemophilus sp.
Primary bacterial resistance to macrolides occurs due to post-translational methylation of 23s bacterial rRNA. Because of mutation, the bacterial resistance is either plasmid-mediated or chromosomal. This results in the cross-resistance of macrolides, streptogramins, and lincosamides. Other two rarely seen acquired resistances are the production of drug-inactivating enzymes, as well as the production of active ATP-dependent proteins which carry the drug outside of the cell.
Macrolide drugs market is expected to have a moderate growth during the forecast period attributing to the increasing prevalence of infectious diseases, in turn increasing the demand for drugs against the infections. Furthermore, a rising elderly population, the alarming rate of increasing number of multi-strain resistant bacterial strains as well as better benefits over the conventional antibiotics are driving factors for the macrolide drugs market. Macrolide drug is good for oral absorption, it is easy for absorption in tissues and also has an easier dosage of once or twice a day. Macrolide drug has very low incidences of side effects. A study stated that macrolide may increase the risk of a sudden cardiac arrest, ventricular tachyarrythmias, and cardiovascular deaths, also GI disorders and inhibition of hepatic metabolism may hinder the growth of macrolide drugs market.
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Based on the type, macrolide drugs market has been segmented into 14-membered ring agents, 14-membered ring agents, 15-membered ring agents (Azalides), 16-membered ring agents, and Ketolides. Based on the sales channel, macrolide drugs market has been segmented into hospitals, clinics, hospital pharmacies, retail pharmacies, and online pharmacies. Based on region, the macrolide drugs market is further segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America is expected to remain the main region over the forecast period. Rising healthcare understanding and awareness about drugs against infections is expected to boost the market in this region. Europe was the second largest market followed by Asia Pacific. Asia Pacific is expected to show the fastest growth rate during the forecast period while Latin America market is projected to grow at a moderate rate during the forecast period. The Middle East and Africa are also expected to experience noticeable growth in the years to come with increasing awareness.
Some of the key players in macrolide drugs market include Abbott Laboratories, Akorn, Inc., Eli Lilly & Co., Fresenius Kabi USA, Gland Pharma Limited, Neo Chemistry, Macrolide Pharmaceuticals, Mylan NV, Pfizer, Inc., Sanofi, Merck & Co., Sandoz International GmbH, Teva Pharmaceutical Industries Ltd., and WOCKHARDT, among others.
This report segments the global macrolide drugs market as follows:
Global Macrolide Drugs Market: By Type
14-membered ring agents
15-membered ring agents (Azalides)
16-membered ring agents
Global Macrolide Drugs Market: By Sales Channel
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Global Macrolide Drugs Market: By Region
The Middle East and Africa